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Results: PA administration showed beneficial effects on APAP-induced hepatotoxicity through improvements in liver functions, decreased CYP2E1 gene expression, decreased serum and liver iron load, decreased MDA, increased GSH, increased SIRT -1 expression level and improvement in hepatic architecture

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Servings:15 Suppositories

Ultrapure water was obtained from a Milli-Q Integral 10 (MilliporeSigma, Burlington, MA, USA) equipped with a 0.22-µm membrane cartridge